We got this room for about $100 on Hotwire. We stayed one night and I would say we had an okay stay. Nothing to write home about.
The room was small, but the beds were really comfy. The carpeting was stained, and little things like the wallpaper peeling in the bathroom makes me think this place needs a little remodeling.
They don't use fitted sheets on their beds which is my pet peeve.
A computer was provided in the room with internet access. We didn't have to pull ours out to check the weather and maps, etc., which was nice.
No complimentary breakfast here. Parking is $15. It's an easy drive to the Visitor Center in Center City (another $15 to park there....)
The front desk staff was very friendly, efficient and professional.
The pool was closed (and will be until May 23rd) unfortunately b/c it was really hot and the kids would've loved to swim.
The walls are a little thin - we could hear the people in the next room banging around, but it was quickly resolved when we called the front desk and complained.
Overall, for $100, it was a good stay. But I would've been pretty disappointed if I had paid the going rate of $288.

We tend to avoid Sheratons and Hiltons. We find them to be overpriced for what they offer. We stayed at the Sheraton University City because of visiting U Penn, a short walk from the hotel.

The check-in was the best part of the stay. The woman who helped us was the most professional and courteous front desk person we ever had.

Supposedly, the hotel was recently renovated. The room had ink stains on the carpeting. The bathroom is small, but adaquate. The coffee maker had stale water in it (we decided not to bother with it after that). There were no tea bags, only coffee (no great loss, I guess, since we weren't going to use the dirty coffeee maker). The linens and towels were fine. Good internet service. The room is large enough for 2 queen beds, but the hotel only offers double beds or kings.

The room was quiet. We faced U Penn, so the views were attarctive. It's conveniently located, with many dining options nearby.

We would grudgingly stay here again if we had to because of the convenience to U Penn, and because the Hilton (which we rate the same as Sheraton) is more expensive. Also, the parking fee at the Sheraton is only $15, while it's $25 at the Hilton. The parking spots were of a good size for our Lexus SUV (contrary to some other comment about the spots being tight).

Pros:
Clean, nicely appointed rooms, free wireless, large screen TV, Beds were very comfortable. Quiet (apart from the occasional siren from the street). Incorrect incidental charges to my Visa were removed as promised (I had to catch a train, so I didn't have time to see that it was resolved in person). Staff were friendly and helpful. Fridge in the room.

Right next door to Starbucks, the street car and a close walk to the subway. A very walkable 6 blocks to the 30th Street Railway Station and about 10 blocks from Trader Joes. You can walk to downtown in about 30 minutes. The area by the train station is a little run down but I walked to downtown and back several times even at night and didn't feel scared at all.

Cons:
Exercise room was disappointing. A collection of old cardio machines, 2 of which were out of order.

I would highly recommend this hotel to visitors to the University of Pennsylvania. It is comfortably furnished, clean, well located, and a great value. There is convenient self parking at a reasonable price. The staff is friendly and helpful.